Granulasi basah. Tujuan granulasi. Formula tablet. R/ Parasetamol mg. Amilum 10% (bahan penghancur) Larutan gelatin 5% (bahan pengikat) Lactosa qs. Parasetamol. aduk hingga larut mg parasetamol (WHO. ).1 N . Metode Pembuatan Tablet Yang Digunakan Yakni Metode Granulasi Basah. Uploaded. DISINTEGRATING TABLET PARASETAMOL DENGAN METODE GRANULASI BASAH. Other thesis, University of Muhammadiyah Malang.

Author: Volkree Gardalabar
Country: Uganda
Language: English (Spanish)
Genre: Environment
Published (Last): 17 April 2013
Pages: 258
PDF File Size: 8.15 Mb
ePub File Size: 2.79 Mb
ISBN: 734-7-32603-234-6
Downloads: 34113
Price: Free* [*Free Regsitration Required]
Uploader: Yolrajas

Extrusion GranulatorExtrusion granulator subclasses primarily are distinguished by theorientation of extrusion surfaces and driving pressure productionmechanism. Evaluasi Serbuk Granulasi Kering Documents.

Amino Granulasi Basah Septa Documents. C SluggingC Roller Compaction2. Whereas, from statistical analysis about friability that was significant difference between F3 with F1 grranulasi F2, but there was no significant difference between F1 with F2.

The physical charateristics of granules including the number of fines, moisture content, flow rate and angle of repose. One of the techniques used to formulate ODT is wet granulation.

Granulasi tools

Wet High-Shear GranulatorWet high-shear granulator subclasses primarily bawah distinguished by thegeometric positioning of the primary impellers; impellers can be top,bottom, or side driven. Granulasi tools Download Report. Wet Low-Shear Granulator16Wet low-shear granulator subclasses primarily are distinguished by thegeometry and design paraseyamol the shear inducing components; shear can beinduced by granluasi impeller, reciprocal kneading action, or convectionscrew action.


In this research the influence of polyplasdone XL as disintegrant on physical characteristics of paracetamol ODT prepared by wet granulation was observed. Spray Dry GranulationA pumpable granulating liquid containing solids in solution orsuspension is atomized in a drying chamber and rapidly dried by acontrolled gas stream, producing a dry powder.

Dasar Teori Granulasi Kering Documents. Extrusion GranulationPlasticization of solids or wetted mass of solids and granulationfluid with linear shear through a sized orifice using a pressure15gradient. Proses tersebut dapat merubah sifat-sifat serbuk seperti: From statistical analysis, it could be seen that there was a significant difference between F1 with F2 and F3, but there was no significant difference between F2 and F3 about hardness bawah disintegration time.

Fluid Bed GranulatorAlthough fluid bed granulators may differ from one another in geometry,operating pressures, and other conditions, no fluid bed granulatorsubclasses have been identified.

Spray Dry Granulator17Although spray dry granulators may differ from one another in geometry,operating pressures, and other conditions. Other thesis, University of Muhammadiyah Malang.

They have either open top architecture, such as a verticalcentrifugal spheronizer, or closed top architecture, such as a closed topfluid bed dryer. This is accomplished bycentrifugal or rotational forces from a central rotating disk, rotatingwalls, or both. Hasil Evaluasi Granulasi Kering Documents.

Serbuk dimodifikasi dengan tambahan bahan pengikat agar saling terikat atau dengan metode dry compaction forces. Teori Dasar Granulasi Kering Parqsetamol. Dry GranulationSerbuk kering didensifikasi dan atau di aglomerasi dengan metode direct physical compactionb. Published on Dec View Download Low-Shear Tumble GranulatorAlthough low-shear tumble granulators may differ from one another invessel geometry and type of dispersion or intensifier bar, no low-sheartumble granulator subclasses have been identified.


Granulasi tools

Jurnal Awal Granulasi Basah Documents. Pembahasan Tr Granulasi Kering Documents.

The number of fines showed good result for all the formulas that were made, while the moisture content were too dry, as well as the flow rate and still has the angle of reposewere very bad. Rotary GranulatorRotary granulator subclasses primarily are distinguished by their structuralarchitecture.

Then the physical characteristics of the tablets were vranulasi. The results showed that increasing the concentrations of polyplasdone XL in the formula causes the decrease in hardnessand disintegration time with increasing friabilityof the tablet.

Lapak Solid Granulasi Basah Documents. Orally disintegrating tablets ODT is a solution for pediatric and geriatric patients who have difficulty in taking oral dosage forms.

Dry GranulatorDry granulator subclasses primarily are distinguished by the densificationforce application mechanism.